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Systane™ Complete Preservative-free

All-In-One Multi-Symptom Dry Eye Relief1,2

Symptoms of Dry Eye can be confusing. They can range from mild irritation to severe discomfort, with varying symptoms including watering, aching, sore and tired eyes1,2. Making it difficult to find a product that meets your needs. Systane Complete Multi Dose Preservative Free eye drops are clinically proven to provide relief for multiple symptoms of dry eye2.

What makes Systane Complete Multi Dose Preservative Free different?



Systane Complete Multi Dose Preservative Free is designed differently using a pH-adaptive Propylene Glycol-Hydroxypropyl-Guar (HP-Guar) nano-sized lipid formula3. When instilled, it forms a hydrophilic
meshwork in the muco-aqueous layer, creating a protective elastic matrix4,5.

This meshwork slowly releases lipid nano-droplets, replenishing the lipid layer of the tear film, enhancing distribution and retention on the ocular surface.

All-In-One Multi-Symptom Relief2,3

To manage multiple symptoms of
dry eye

1 Drop, 8-Hours of Relief3

For rapid, sustained relief from the
first drop

With the Power of HP-Guar

Systane’s HP-Guar formula adapts to your eye’s unique needs3,4

Who is Systane Complete Preservative Free suitable for?

   Moderate Dry Eye Sufferers
   Mixed Type Dry Eye
   Evaporative Dry Eye
   Diabetic Patients suffering from Dry Eye

How to use Systane Complete
Preservative Free?

1. Wash and dry your hands. Shake the bottle well before first opening

2. Tilt your head back and gently pull your eyelid to form a pocket

3. Gently squeeze the bottle to allow 1 drop into the pocket. Keep the tip of the bottle untouched

Clinically proven, multi-symptom Dry Eye relief2

For your first line recommendation

Protects & replenishes
 ALL LAYERS of the tear film1

Relieves all types of Dry 
Eye for up to 8 HOURS1

97% of patients rated their experience with Systane COMPLETE as good/excellent3

References

Consult your healthcare or eye care professional for use, precautions, warnings and contraindications.

1. Bickle K et al. Ophthalmol Ther 13, 481-494 (2024).2. Silverstein S et al, Clin Ophthalmol, 2020;14:3167-3177.3. Silverstein S, Yeu E, Tauber J, Guillon M, Jones L, Galarreta D, Srinivasan S, Manoj V. Symptom Relief Following a Single Dose of Propylene col-Hydroxypropyl Guar Nanoemulsion in Patients with Dry Eye Disease: A Phase IV, Multicenter Trial. Clin Ophthalmol. 2020;14:3167-31774. Ng A, Keech A, Jones L. Tear osmolarity changes after use of hydroxypropyl-guar-based lubricating eye drops. Clin Ophthalmol. 2018 Apr 10;12:695-700.5. Petricek I, Berta A, et al. Hydroxypropyl-guar gellable lubricant eye drops for dry eye treatment. Expert Opin Pharmacother. 2008 Jun;9(8):1431-6.